Left on the doorstep of an orphanage run by nuns at birth, three friends Moe, Larry and Curly spend their time eye poking and slapping each other all the day long. But when their orphanage suddenly goes bankrupt, the three Stooges set out to save it by journeying into the world to find a way to raise the money required. But their quest brings them into being used in a murder scheme and landing them into a popular reality show.